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We reviewed 3 live results for methyl seq and narrowed them down to the 3 options that look most worth comparing first.
The options are Bisulfite Sequencing (Methyl-Seq) Service, NEBNext Enzymatic Methyl-seq (EM-seq) and Methylation Sequencing.
Source: Epigentek
Description
EpiGentek provides Bisulfite Sequencing (Methyl-Seq) Service offering genome-wide, base-resolution DNA methylation analysis. Utilizing next-generation sequencing platforms, the end-to-end service encompasses Targeted Bisulfite Sequencing, Reduced Representation Bisulfite Sequencing (RRBS), and Whole Genome Bisulfite Sequencing (WGBS). The workflow accepts DNA, cell, and tissue samples, delivering complete conversion, rapid 4–8 week turnaround, multi-stage quality control checks, guaranteed Q30 > 75% scores, and bioinformatics deliverables including FASTQ raw files, Bismark read mapping, and differential methylation analysis.
Best for
epigenetics researchers, genomics scientists, performing genome-wide base-resolution DNA methylation profiling and analyzing differential methylation and CpG site frequency
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Source: New England Biolabs France
Description
NEBNext Enzymatic Methyl-seq (EM-seq) by New England Biolabs France is an enzyme-based method for methylome analysis and identification of 5mC and 5hmC as an alternative to bisulfite sequencing. The method utilizes enzymatic conversion with TET2 and APOBEC to minimize DNA damage and GC bias while providing uniform GC coverage, larger library insert sizes, and high library yields from as little as 10 ng input DNA for Illumina and other next-generation sequencing workflows.
Best for
genomics researchers, molecular biology laboratories, methylome analysis and 5mC and 5hmC identification
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Source: GENEWIZ from Azenta
Description
Methylation Sequencing (Methyl-Seq) by GENEWIZ from Azenta Life Sciences provides complete wet and dry lab solutions to quantify DNA methylation and explore the methylome through whole genome or targeted 5-methylcytosine (5mC) detection. The service includes sample protection, enzymatic conversion, library preparation, 2×150 bp sequencing on Illumina platforms, and data analysis, backed by dedicated Ph.D.-level support and turnaround times as fast as two weeks.
Best for
Researchers, Molecular biologists, Quantifying DNA methylation and Epigenetic gene regulation studies
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| Compare | #1Bisulfite Sequencing (Methyl-Seq) Service | #2NEBNext Enzymatic Methyl-seq (EM-seq) | #3Methylation Sequencing |
|---|---|---|---|
| Source | Epigentek | New England Biolabs France | GENEWIZ from Azenta |
| Description | EpiGentek provides Bisulfite Sequencing (Methyl-Seq) Service offering genome-wide, base-resolution DNA methylation analysis. Utilizing next-generation sequencing platforms, the end-to-end service encompasses Targeted Bisulfite Sequencing, Reduced Representation Bisulfite Sequencing (RRBS), and Whole Genome Bisulfite Sequencing (WGBS). The workflow accepts DNA, cell, and tissue samples, delivering complete conversion, rapid 4–8 week turnaround, multi-stage quality control checks, guaranteed Q30 > 75% scores, and bioinformatics deliverables including FASTQ raw files, Bismark read mapping, and differential methylation analysis. | NEBNext Enzymatic Methyl-seq (EM-seq) by New England Biolabs France is an enzyme-based method for methylome analysis and identification of 5mC and 5hmC as an alternative to bisulfite sequencing. The method utilizes enzymatic conversion with TET2 and APOBEC to minimize DNA damage and GC bias while providing uniform GC coverage, larger library insert sizes, and high library yields from as little as 10 ng input DNA for Illumina and other next-generation sequencing workflows. | Methylation Sequencing (Methyl-Seq) by GENEWIZ from Azenta Life Sciences provides complete wet and dry lab solutions to quantify DNA methylation and explore the methylome through whole genome or targeted 5-methylcytosine (5mC) detection. The service includes sample protection, enzymatic conversion, library preparation, 2×150 bp sequencing on Illumina platforms, and data analysis, backed by dedicated Ph.D.-level support and turnaround times as fast as two weeks. |
| Best for | epigenetics researchers, genomics scientists, performing genome-wide base-resolution DNA methylation profiling and analyzing differential methylation and CpG site frequency | genomics researchers, molecular biology laboratories, methylome analysis and 5mC and 5hmC identification | Researchers, Molecular biologists, Quantifying DNA methylation and Epigenetic gene regulation studies |
| Action | Epigentek | New England Biolabs France | GENEWIZ from Azenta |
| Rate this product |
"Bisulfite Sequencing (Methyl-Seq) Service from Epigentek."
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