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We reviewed 3 live results for em seq and narrowed them down to the 3 options that look most worth comparing first.
The options are WGBS (Whole Genome Bisulfite Sequencing) and EM-seq (Enzymatic Methylation) Service, NEBNext Enzymatic Methyl-seq (EM-seq) and Bisulfite Sequencing (Methyl-Seq) Service.
Source: Diagenode
Description
Diagenode provides comprehensive WGBS (Whole Genome Bisulfite Sequencing) and EM-seq (Enzymatic Methylation) services for in-depth, genome-wide DNA methylation profiling at single-nucleotide resolution. The end-to-end workflow spans genomic DNA quality control, library preparation, and deep paired-end sequencing on Illumina platforms, detecting over 50 million CpGs across human, mouse, and rat samples. It supports low input, cfDNA, and FFPE specimens, with dedicated scientist guidance and optional bioinformatics analysis including differential methylation, pathway analysis, and biomarker data mining.
Best for
epigenomics researchers, biomarker discovery scientists, genome-wide DNA methylation profiling and single-nucleotide resolution epigenetic analysis
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Source: New England Biolabs France
Description
NEBNext Enzymatic Methyl-seq (EM-seq) by New England Biolabs France is an enzyme-based method for methylome analysis and identification of 5mC and 5hmC as an alternative to bisulfite sequencing. The method utilizes enzymatic conversion with TET2 and APOBEC to minimize DNA damage and GC bias while providing uniform GC coverage, larger library insert sizes, and high library yields from as little as 10 ng input DNA for Illumina and other next-generation sequencing workflows.
Best for
genomics researchers, molecular biology laboratories, methylome analysis and 5mC and 5hmC identification
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Source: Epigentek
Description
EpiGentek provides Bisulfite Sequencing (Methyl-Seq) Service offering genome-wide, base-resolution DNA methylation analysis. Utilizing next-generation sequencing platforms, the end-to-end service encompasses Targeted Bisulfite Sequencing, Reduced Representation Bisulfite Sequencing (RRBS), and Whole Genome Bisulfite Sequencing (WGBS). The workflow accepts DNA, cell, and tissue samples, delivering complete conversion, rapid 4–8 week turnaround, multi-stage quality control checks, guaranteed Q30 > 75% scores, and bioinformatics deliverables including FASTQ raw files, Bismark read mapping, and differential methylation analysis.
Best for
epigenetics researchers, genomics scientists, performing genome-wide base-resolution DNA methylation profiling and analyzing differential methylation and CpG site frequency
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| Compare | #1WGBS (Whole Genome Bisulfite Sequencing) and EM-seq (Enzymatic Methylation) Service | #2NEBNext Enzymatic Methyl-seq (EM-seq) | #3Bisulfite Sequencing (Methyl-Seq) Service |
|---|---|---|---|
| Source | Diagenode | New England Biolabs France | Epigentek |
| Description | Diagenode provides comprehensive WGBS (Whole Genome Bisulfite Sequencing) and EM-seq (Enzymatic Methylation) services for in-depth, genome-wide DNA methylation profiling at single-nucleotide resolution. The end-to-end workflow spans genomic DNA quality control, library preparation, and deep paired-end sequencing on Illumina platforms, detecting over 50 million CpGs across human, mouse, and rat samples. It supports low input, cfDNA, and FFPE specimens, with dedicated scientist guidance and optional bioinformatics analysis including differential methylation, pathway analysis, and biomarker data mining. | NEBNext Enzymatic Methyl-seq (EM-seq) by New England Biolabs France is an enzyme-based method for methylome analysis and identification of 5mC and 5hmC as an alternative to bisulfite sequencing. The method utilizes enzymatic conversion with TET2 and APOBEC to minimize DNA damage and GC bias while providing uniform GC coverage, larger library insert sizes, and high library yields from as little as 10 ng input DNA for Illumina and other next-generation sequencing workflows. | EpiGentek provides Bisulfite Sequencing (Methyl-Seq) Service offering genome-wide, base-resolution DNA methylation analysis. Utilizing next-generation sequencing platforms, the end-to-end service encompasses Targeted Bisulfite Sequencing, Reduced Representation Bisulfite Sequencing (RRBS), and Whole Genome Bisulfite Sequencing (WGBS). The workflow accepts DNA, cell, and tissue samples, delivering complete conversion, rapid 4–8 week turnaround, multi-stage quality control checks, guaranteed Q30 > 75% scores, and bioinformatics deliverables including FASTQ raw files, Bismark read mapping, and differential methylation analysis. |
| Best for | epigenomics researchers, biomarker discovery scientists, genome-wide DNA methylation profiling and single-nucleotide resolution epigenetic analysis | genomics researchers, molecular biology laboratories, methylome analysis and 5mC and 5hmC identification | epigenetics researchers, genomics scientists, performing genome-wide base-resolution DNA methylation profiling and analyzing differential methylation and CpG site frequency |
| Action | Diagenode | New England Biolabs France | Epigentek |
| Rate this product |
"WGBS (Whole Genome Bisulfite Sequencing) and EM-seq (Enzymatic Methylation) Service from Diagenode."
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