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We reviewed 3 live results for heterobifunctional and narrowed them down to the 3 options that look most worth comparing first.
The options are SATA Crosslinker Reagent, SATA and Pierce™ Sulfhydryl Addition Kit.
Source: Cyanagen
Description
SATA Crosslinker Reagent (product code E050N) by Cyanagen is a short-chain heterobifunctional reagent with a 2.8 angstrom spacer arm designed for covalent modification of primary amines with a protected sulfhydryl group. It reacts at pH 7–9 to introduce a stable protected thiol that can be deprotected using hydroxylamine-HCl for biomolecule conjugation and protein chemistry applications.
Best for
biochemists, laboratory researchers, protein chemistry modification and biomolecule crosslinking
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Source: Soltec Ventures
Description
SATA (N-Succinimidyl-S-acetylthioacetate) is a short-chain protein modification reagent featuring a 2.8 angstrom spacer arm designed to introduce protected thiol groups onto primary amines such as lysine residues and protein amino termini. Offered by Soltec Ventures, it enables heterobifunctional crosslinking strategies and long-term storage of sulfhydryl-modified biomolecules without dipeptide formation, deprotecting with hydroxylamine for conjugation to maleimide-modified proteins under mild, non-denaturing conditions.
Best for
Protein biology researchers, Biochemical assay developers, Introducing protected sulfhydryl groups onto primary amines and Heterobifunctional protein crosslinking without dipeptide formation
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Source: Thermo Fisher Scientific
Description
The Thermo Scientific Pierce Sulfhydryl Addition Kit provides all necessary reagents and components to introduce protected, exposable free sulfhydryl groups into primary amine-containing molecules such as proteins and peptides. Utilizing SATA reagent with a 2.8 angstrom spacer arm, it enables covalent modification, purification, and quantification of added sulfhydryl groups for heterobifunctional crosslinking workflows under mild, non-denaturing conditions for research use.
Best for
researchers, biochemists, introducing sulfhydryl groups into proteins and heterobifunctional crosslinking
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| Compare | #1SATA Crosslinker Reagent | #2SATA | #3Pierce™ Sulfhydryl Addition Kit |
|---|---|---|---|
| Source | Cyanagen | Soltec Ventures | Thermo Fisher Scientific |
| Description | SATA Crosslinker Reagent (product code E050N) by Cyanagen is a short-chain heterobifunctional reagent with a 2.8 angstrom spacer arm designed for covalent modification of primary amines with a protected sulfhydryl group. It reacts at pH 7–9 to introduce a stable protected thiol that can be deprotected using hydroxylamine-HCl for biomolecule conjugation and protein chemistry applications. | SATA (N-Succinimidyl-S-acetylthioacetate) is a short-chain protein modification reagent featuring a 2.8 angstrom spacer arm designed to introduce protected thiol groups onto primary amines such as lysine residues and protein amino termini. Offered by Soltec Ventures, it enables heterobifunctional crosslinking strategies and long-term storage of sulfhydryl-modified biomolecules without dipeptide formation, deprotecting with hydroxylamine for conjugation to maleimide-modified proteins under mild, non-denaturing conditions. | The Thermo Scientific Pierce Sulfhydryl Addition Kit provides all necessary reagents and components to introduce protected, exposable free sulfhydryl groups into primary amine-containing molecules such as proteins and peptides. Utilizing SATA reagent with a 2.8 angstrom spacer arm, it enables covalent modification, purification, and quantification of added sulfhydryl groups for heterobifunctional crosslinking workflows under mild, non-denaturing conditions for research use. |
| Best for | biochemists, laboratory researchers, protein chemistry modification and biomolecule crosslinking | Protein biology researchers, Biochemical assay developers, Introducing protected sulfhydryl groups onto primary amines and Heterobifunctional protein crosslinking without dipeptide formation | researchers, biochemists, introducing sulfhydryl groups into proteins and heterobifunctional crosslinking |
| Action | Cyanagen | Soltec Ventures | Thermo Fisher Scientific |
| Rate this product |
"SATA Crosslinker Reagent from Cyanagen."
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